Aldosterone, a mineralocorticoid steroid hormone from the adrenal cortex, is the primary long-term regulator of sodium reabsorption in the principal cells of the kidney's collecting duct and distal tubule. It acts by stimulating the synthesis and insertion of epithelial sodium channels (ENaC) and Na+/K+ ATPase pumps into the cell membranes. This increases the reabsorption of Na+ from the tubular fluid into the blood. Chloride follows sodium electrostatically, and water follows osmotically, leading to an expansion of extracellular fluid volume and an increase in blood pressure. Simultaneously, aldosterone promotes the secretion of potassium (K+) and hydrogen ions (H+) into the urine. Its secretion is primarily controlled by the Renin-Angiotensin-Aldosterone System (RAAS) in response to low blood pressure, volume, or high potassium.

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Zambia

• loveness Phiri – 1084 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies