University revision · Immunology

Tumour Antigens

Question 1 of 5 Course: Biomedical Science(Degree)

Tumor antigens that are unique to tumor cells and arise from mutations are called Tumor-Specific Transplantation Antigens (TSTAs).

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This statement is true. A leukoerythroblastic blood picture (or leukoerythroblastic reaction) is a significant finding on a peripheral blood smear. It describes the presence of both immature cells from the white cell line (such as myelocytes, metamyelocytes, and even promyelocytes or blasts) and immature cells from the red cell line (nucleated red blood cells or erythroblasts). These are cells that are not normally seen in the circulating blood of healthy adults. This picture suggests that the bone marrow is under severe stress or that its normal architecture has been disrupted, allowing these immature precursors to 'spill over' into the blood. It is classically associated with conditions like bone marrow infiltration (by cancer, fibrosis, or granulomas), severe hemolytic anemias, or myelophthisis.

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