Vestibular System Physiology
Q: What is the primary mechanism by which the vestibular apparatus detects rotational acceleration?
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Buprenorphine is a partial agonist at the mu-opioid receptor. It has a high affinity but low intrinsic activity, which means it can provide analgesia and treat opioid dependence with a ceiling effect on respiratory depression, making it safer in overdose compared to full agonists.
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