Viral Oncogenesis Mechanisms
This advanced topic delves into the molecular and cellular mechanisms by which viruses contribute to cancer development. It covers direct mechanisms, such as viral oncogenes (e.g., HPV E6/E7, EBV LMP1) inactivating tumor suppressors (p53, Rb), and indirect mechanisms, such as chronic inflammation and immune modulation (e.g., HBV/HCV). For Zambian university students in molecular biology, genetics, and pathology, this knowledge is crucial for understanding cancer aetiology, molecular diagnostics, and targeted therapies. It represents a high level of integration between virology and oncology, essential for research and advanced clinical practice.
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