Warfarin Poisoning and Reversal
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Long-term NSAID use can cause: 1) Acute interstitial nephritis (allergic reaction). 2) Papillary necrosis (due to medullary ischemia). 3) Chronic kidney disease (from prolonged vasoconstriction). 4) Sodium and water retention (edema, hypertension). 5) Hyperkalemia (reduced renin release).
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