Glucagon, secreted by pancreatic alpha cells in response to low blood glucose, acts primarily on the liver to increase blood sugar levels. Its main hepatic effects are: 1) Stimulating glycogenolysis: It activates enzymes that break down glycogen (the stored form of glucose) into glucose-1-phosphate, which is then converted to glucose-6-phosphate and released as free glucose into the bloodstream. 2) Stimulating gluconeogenesis: It promotes the synthesis of new glucose from non-carbohydrate precursors like amino acids (from protein breakdown) and glycerol (from fat breakdown). Glucagon also inhibits glycogen synthesis and promotes ketogenesis in the liver during prolonged fasting. These actions are precisely opposite to those of insulin, making glucagon essential for preventing hypoglycemia between meals and during fasting.

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Zambia

• loveness Phiri – 1084 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies