Gene Delivery Systems in Gene Therapy

Gene delivery systems are a technical and applied topic in gene therapy for Zambian university and college students in biotechnology, genetics, and biomedical engineering programs. This subject covers the various vectors and methods used to introduce therapeutic genes into target cells, including viral vectors (adenovirus, retrovirus, lentivirus, adeno-associated virus) and non-viral methods (naked DNA, liposomes, receptor-mediated delivery). Students will compare the advantages, limitations, and safety profiles of each system, and explore current clinical applications. The content is tailored to tertiary education in Zambia, supporting curriculum goals for practical and theoretical knowledge in advanced genetics. Mastery of gene delivery systems prepares learners for careers in genetic research, biopharmaceuticals, and clinical trial management, contributing to the advancement of personalized medicine and therapeutic innovations in Zambia's healthcare landscape.